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Liping Zhao

Appointment

  • Fellow
  • Humans & the Microbiome

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About

Liping Zhao is currently the Eveleigh-Fenton Chair of Applied Microbiology at Department of Biochemistry and Microbiology, School of Environmental and Biological Sciences, Rutgers University. He is a fellow of American Academy of Microbiology and serves on the Scientific Advisory Board for the Center for Microbiome Research and Education of American Gastroenterology Association (AGA).

His team has pioneered the approach of applying metagenomics-metabolomics integrated tools and dietary intervention for systems understanding and predictive manipulation of gut microbiota to improve human metabolic health. Following the logic of Koch’s postulates, Liping has found that an endotoxin-producing opportunistic pathogen isolated from an obese human gut can induce obesity in germfree mice. Their clinical trials published in Science and EBioMedicine showed that dietary modulation of gut microbiota can significantly alleviate metabolic diseases including a genetic form of obesity in children and type 2 diabetes in adults.  Science magazine featured a story on how he combines traditional Chinese medicine and gut microbiota study to understand and fight obesity (Science 336: 1248).

Awards

  • Rutgers University Eveleigh-Fenton Chair of Applied Microbiology
  • Fellow of the American Academy of Microbiology
  • Scientific Advisory Board member for the Center for Microbiome Research and Education of American Gastroenterology Association (AGA).

Relevant Publications

  • Zhao, L., Zhang, F., Ding, X., Wu, G., et al. (2018). Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes. Science, 359, 1151-1156. PMID:29590046
  • Zhang C., Yin, A. Li, H., Wu, G.,...Zhao, L. (2015). Dietary modulation of gut microbiota contributes to alleviation of both genetic and simple obesity in children. EBioMedicine, 2(8), 968-84. DOI: 10.1016/j.ebiom.2015.07.007. PMCID: PMC4563136
  • Fei, N., & Zhao, L. (2013). An opportunistic pathogen from the gut of an obese human causes obesity in germfree mice. ISME J, 7(4), 880–884. PMCID: PMC3603399
  • Zhao, L. (2013). The gut microbiota and obesity: from correlation to causality. Nat Rev Microbiol, 11(9): 639-647. PMID:23912213
  • Li, M., Wang, B., Zhang, M., Rantalainen, M., Wang S.,... Zhao, L. (2008). Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci USA, 105(6): 2117-2122. PMCID:PMC2538887

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