Philippe Gros’ research seeks out genes, proteins and pathways in mice that relate to complex human diseases.
He focuses on infectious disease, cancer and the birth defect spina bifida, which causes underdevelopment in the spinal cord and the bones around it. He studies the genetic factors that may predispose us to disease, cause it, or result in drug resistance during treatment. Gros and his team aim to create diagnostic tools and small molecule drugs to help treat diseases, using the knowledge gained from their studies of mice and zebra fish.
- McLaughlin Medal for Scientific Excellence, Royal Society of Canada, 2014
- Queen Elizabeth II Diamond Jubilee Medal, Association of Universities and Colleges of Canada, 2013
- Killam Prize in Health Sciences, Canada Council for the Arts, 2009
- Prix Wilder-Penfield, Government of Quebec, 2008
- Fellow of the Royal Society of Canada, 2003
Torre, S., Faucher, S.P., Fodil, N.,…Gros, P. (2015). THEMIS is required for pathogenesis of cerebral malaria and for protection against pulmonation tuberculosis. Infection and Immunity, 82(2), 759–68. DOI: 10.1128/IAI.02586-14
Zhang, X., Bogunovic, D., Payelle-Brogard, B.,…Gros, P. (2015). Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation. Nature, 517(7532), 89-93. DOI: 10.1038/nature13801
Gros, P., & Belkaid, Y. (2014). Editorial Overview: Host pathogens. Current Opinion Immunology, 29, iv–vi. DOI: 10.1016/j.coi.2014.06.008.
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