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Arturo Casadevall

Appointment

Advisor

Fungal Kingdom: Threats & Opportunities

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About

Arturo Casadevall is a molecular biologist, immunologist, and infectious diseases physician who has been working on the problem of microbial pathogenesis for over two decades.

The author of over 780 publications, the primary focus of his research is the human pathogenic fungus Cryptococcus neoformans. His laboratory has broad interests in the area of infectious diseases and has also studied Bacillus anthracis and Mycobacterium tuberculosis.

Casadevall is also interested in the problems with scientific enterprise and with collaborators showed that misconduct accounts for the majority of retracted publications. He is editor-in-chief of mBio, Deputy Editor of the Journal of Clinical Investigation and serves on several numerous editorial boards. He has served on several NIH committees including the NIAID Strategic Plan, the Blue Ribbon Panel on Biodefense Research, the NAS panel that reviewed the FBI investigation on anthrax attacks, the NAS Federal Regulations and Reporting committee and the National Science Advisory Board for Biosecurity. He was a Commissioner in the National Commission on Forensic Science and previously served as President of the Medical Mycology Society of the Americas.

Awards

  • National Academy of Sciences, 2022
  • Member, American Academy of Arts and Sciences, 2017
  • Member, National Academy of Medicine, 2014
  • Fellow, American Association for the Advancement of Science, 2006
  • Member, Association of American Physicians, 2004
  • Fellow, American Academy of Microbiology, 2002

Relevant Publications

  • Cordero, R., Robert, V., Cardinali,… & Casadevall, A. (2018). Impact of yeast pigmentation on heat capture and latitudinal distribution. Current Biology, 28(16), 2657–2664.e3. DOI:10.1016/j.cub.2018.06.034

  • Casadevall, A., Pirofski, L.A. (2011). A new synthesis for antibody-mediated immunity. Nat Immunol, 13(1), 21-28. DOI: 10.1038/ni.2184.

  • Rodrigues, M.L., Nimrichter, L., Oliveira, D.L., … Casadevall, A. (2007). Vesicular polysaccharide export in cryptococcus neoformans is a eukaryotic solution to the problem of fungal trans-cell wall transport. Eukaryotic Cell, 6(1), 48–59. DOI:10.1128/EC.00318-06

  • Steenbergen, J.N., Shuman, H.A., & Casadevall, A. (2001). Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proceedings of the National Academy of Sciences of the United States of America, 98(26), 15245–15250. DOI:10.1073/pnas.261418798

  • Mukherjee, J., Nussbaum, G., Scharff, M.D., & Casadevall, A. (1995). Protective and nonprotective monoclonal antibodies to cryptococcus neoformans originating from one B cell. The Journal of experimental medicine, 181(1), 405–409. DOI:10.1084/jem.181.1.405

Institution

Johns Hopkins University

Education

  • MD (Medicine), New York University
  • PhD (Physical Biochemistry) , New York University
  • MS (Biochemistry), New York University
  • BA (Chemistry), Queens College

Country

United States

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The Canadian Institute for Advanced Research (CIFAR) is a globally influential research organization proudly based in Canada. We mobilize the world’s most brilliant people across disciplines and at all career stages to advance transformative knowledge and solve humanity’s biggest problems, together. We are supported by the governments of Canada, Alberta and Québec, as well as Canadian and international foundations, individuals, corporations and partner organizations.

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