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Charles M. Boone


  • Program Co-Director
  • Fellow
  • Fungal Kingdom: Threats & Opportunities
  • Genetic Networks


Boone Lab


Charles Boone is a molecular biologist. He has implemented an automated form of yeast genetic analysis to cross thousands of specific strains carrying precise mutations and to map yeast genetic interactions on a large scale.

The global genetic interaction network maps a functional wiring diagram of the cell, clustering genes into specific pathways to reveal their functional connections. An understanding of the general principles of genetic networks in the yeast model system provides a framework for exploring genetic interactions in the context of human genetics.


  • Genetics Society of America (GSA) Edward Novitski Prize, Creativity in Genetics, 2014
  • Emil Christian Hansen Award for Microbiology, Carlsberg Foundation (shared with Brenda Andrews), 2013
  • Fellow, American Academy of Microbiology, 2012 to present
  • Honorary Doctorate, University of Gothenburg, 2011
  • Fellow of the American Association for the Advancement of Science, 2011 to present
  • Tier 1 Canada Research Chair in Proteomics, Bioinformatics and Functional Genomics, 2007 to present

Relevant Publications

  • Costanzo, M. et al. “The genetic landscape of a cell.” Science 27, no. 5964 (2010): 425–31.

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