About
The Chang group works at the interface of biocatalysis and synthetic biology. Our interest is to discovery, characterize, and engineer enzymes, metabolic pathways, and cells for applications in sustainable chemistry.
Awards
- Centenary Prize, Royal Society of Chemistry, 2022
- Pfizer Award in Enzyme Chemistry, ACS Division of Biological Chemistry, 2016
- Arthur C. Cope Scholar Award, ACS, 2015
- DARPA Young Faculty Award, US DOD, 2012
- Beckman Young Investigator Award, Beckman Foundation, 2008
Relevant Publications
- Thevasundaram, K., Gallagher, J.J., Cherng, F. & Chang, M.C.Y. (2022) Engineering non-photosynthetic carbon fixation for production of bioplastics by methanogenic archaea, Proc. Natl. Acad. Sci. U.S.A. 119 (23), e2118638119. DOI: 10.1073/pnas.2118638119
- Wang, Z.Q., Song, H., Koleski, E.J., Hara, N., Park, D.S., Kumar, G., Min, Y., Dauenhauer, P.J. & Chang, M.C.Y. (2021) A dual cellular-heterogeneous catalyst strategy for the production of olefins from glucose, Nat. Chem. 13, 1178-1185. DOI: 10.1038/s41557-021-00820-0
- Dong, H., Liffland, S., Hillmyer, M.A. & Chang, M.C.Y. (2019) Engineering in vivo production of α-branched polyesters, J. Am. Chem. Soc. 141(42), 16877-16883. DOI: 10.1021/jacs.9b08585