My lab aims to understand how the ~37 trillion cells of the human body interact and assemble to make functioning tissues and organs. We develop cutting edge techniques in single cell and spatial genomics to precisely measure which genes are turned on in individual cells, map where these cells are located within tissues, and determine how they interact with other cells. In our resulting ‘cell atlases’, we have mapped millions of cells across the body, with a particular focus on the distributed immune system. We have discovered new cell types, developmental pathways and tissue microenvironments, and unpicked the cellular basis of various diseases from COVID-19 to cancer. My lab is part of the Human Cell Atlas, an international consortium aiming to map every cell type of the human body which I co-founded with fellow MUH Fellow Aviv Regev in 2016.
- FEBS | EMBO Women in Science Award, 2023
- Fellow, Royal Society, 2020
- Fellow, Academy of Medical Sciences, 2015
- EMBO Gold Medal, 2015
- Lister Research Prize, 2010
- Vento-Tormo R, et al. (2018). Single-cell reconstruction of the early maternal-fetal interface in humans. Nature. Nov;563(7731):347-353. doi: 10.1038/s41586-018-0698-6
- Sungnak W, et al. (2020) SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nature Medicine. May;26(5):681-687. doi: 10.1038/s41591-020-0868-6
- Suo C, Dann E, et al. (2022). Mapping the developing human immune system across organs. Science. Jun 3;376(6597):eabo0510. doi: 10.1126/science.abo0510
CIFAR is a registered charitable organization supported by the governments of Canada, Alberta and Quebec, as well as foundations, individuals, corporations and Canadian and international partner organizations.