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Eilif Muller-BW_F

Eilif B. Muller


  • Canada CIFAR AI Chair
  • Pan-Canadian AI Strategy


Google Scholar


Eilif Muller is an IVADO assistant research professor in the department of neurosciences at the University of Montreal, a principle investigator of the Architectures of Biological Learning Lab (ABL-Lab) at the CHU Sainte-Justine Research Center, and associate faculty member at Mila. His research tackles a fundamental mystery at the intersection of neuroscience and artificial intelligence: how sensory perception is learned in the neocortex. Integrating the latest empirical advances in our understanding of the synaptic, dendritic, and circuit physiology of the neocortex, the ABL-Lab leverages a synergy of biophysical simulations of neocortical circuits and functional deep convolutional networks to explore a radically new dendritic perspective on the processes of neocortical learning.  The aim is to understand how the neocortex can learn continually from only a few labeled examples and robustly generalize to others, and provide new inspiration to solve these open challenges in the field of deep learning.


  • IVADO Professor, 2020

Relevant Publications

  • Chindemi, G., Abdellah, M., Amsalem, O., Benavides-Piccione, R., Delattre, V., Doron, M., ... & Müller, E. B. (2020). A calcium-based plasticity model predicts long-term potentiation and depression in the neocortex. bioRxiv.
  • Nolte, M., Reimann, M. W., King, J. G., Markram, H., & Muller, E. B. (2019). Cortical reliability amid noise and chaos. Nature communications, 10(1), 1-15.
  • Reimann, M. W., Gevaert, M., Shi, Y., Lu, H., Markram, H., & Muller, E. (2019). A null model of the mouse whole-neocortex micro-connectome. Nature communications, 10(1), 1-16.
  • Markram, H., Muller, E., Ramaswamy, S., Reimann, M. W., Abdellah, M., Sanchez, C. A., ... & Schürmann, F. (2015). Reconstruction and simulation of neocortical microcircuitry. Cell, 163(2), 456-492.
  • Delattre, V., Keller, D., Perich, M., Markram, H., & Muller, E. B. (2015). Network-timing-dependent plasticity. Frontiers in cellular neuroscience, 9, 220.

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CIFAR is a registered charitable organization supported by the governments of Canada, Alberta and Quebec, as well as foundations, individuals, corporations and Canadian and international partner organizations.

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