Iuliana V. Ene
Appointment
CIFAR Azrieli Global Scholars 2021-2023
Fungal Kingdom: Threats & Opportunities
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About
As a molecular mycologist, Iuliana Ene is interested in identifying and addressing current challenges in tackling human fungal infections. There is a dire need of improved diagnostics and novel therapies. Emerging fungal threats, including recent outbreaks in human and animal populations, have intensified these needs. Ene’s research seeks to advance our fundamental understanding of how fungi interact with their hosts, how they adapt to challenges posed by our host defence systems, and how they escape and adapt to antifungal therapy. She also aims to leverage this knowledge for the development of improved therapeutic strategies.
Awards
- Vessa Notchev Postdoctoral Fellowship, Graduate Women in Science, 2014
- Principal’s Excellence Award, University of Aberdeen, 2012
- Marie Curie PhD Training Fellow, European Commission, 2009
- Craig Teaching and Research Award, Brown University, 2009
Relevant Publications
Ene, I. V. et al. (2018). Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen. Proc Natl Acad Sci U S A, 115 (37) E8688-E8697. DOI:10.1073/pnas.1806002115.
Rosenberg, A., Ene, I. V., Bibi, M., Zakin, S., Segal, E. S., Ziv, N., … & Berman, J. (2018). Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia. Nature communications, 9(1), 1-14.
Ene, I. V. et al. (2012). Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen. Cellular microbiology, 14, 1319-1335, DOI:10.1111/j.1462-5822.2012.01813.x.
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